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TVial Liquid Filling Sealing Production Line is a fully automated pharmaceutical processing system designed specifically for rigorous cleanroom environments.
The integrated system comprises an ultrasonic vial washer, a tunnel sterilizer/dryer, a precision liquid filling unit, a stoppering mechanism, and a capping machine.
The modules work in concert to execute a continuous sequence of operations: spraying, ultrasonic cleaning, internal and external rinsing, preheating, sterilization, depyrogenation, cooling, vial alignment, nitrogen purging (pre-fill), liquid filling, nitrogen purging (post-fill), stoppering, and final capping.
All core components in contact with the pharmaceutical product are constructed from 316L stainless steel and feature durable PTFE (Teflon) seals; the surfaces are smooth, easy to clean, and resistant to corrosive medications. The entire system is designed and manufactured in strict accordance with cGMP and FDA standards, ensuring a sterile, compliant, and highly efficient production process.
Parameter | Specification |
|---|---|
Applicable Container | Pharmaceutical glass vials |
Typical Vial Range | 2–25 mL or customized |
Applicable Product | Sterile pharmaceutical liquids |
Main Processes | Washing, drying, sterilizing, depyrogenation, filling, stoppering and capping |
Washing Method | Ultrasonic cleaning with internal and external air-water flushing |
Sterilization Method | Hot-air circulation tunnel |
Filling System | Selected according to product and capacity |
Nitrogen Flushing | Optional |
Stoppering | Automatic |
Capping | Automatic |
Control System | PLC and touchscreen HMI |
Line Control | Full-line linkage |
Independent Operation | Individual machines can operate separately |
Aseptic Protection | Laminar airflow, RABS or isolator options |
Production Capacity | Confirm according to selected line |
Filling Accuracy | Confirm according to pump system and product |
Layout | Straight-line or customized |
Downstream Connection | Inspection, labeling and cartoning equipment |